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H-1B Sponsor Profile

Shire Human Genetic Therapies Inc. — H-1B Visa Sponsorship Data

101 certified Labor Condition Applications on file with the U.S. Department of Labor, FY2021–FY2026.

Lexington, MAActive FY2021–FY2026Transfer-FriendlyFull-Time RolesNot H-1B Dependent
● Data current through FY2026 · sourced from U.S. DOL OFLC, updated quarterly
I work at Shire Human Genetic Therapies Inc.See what a DOL auditor would ask about your filingsConsidering a job here?Salaries, transfers and where roles are based
Sponsors H-1B?
Yes
101 certified LCAs
FY2026 filings
6
most recent disclosure year
Median H-1B salary
$123,000
typical $106,012–$152,193
H-1B dependent?
No
per the employer's LCA attestation
Transfer share
27%
change-of-employer filings
Audit readiness Check another employer

4 items a DOL auditor would ask Shire Human Genetic Therapies Inc. about

Since September 2025, DOL's Project Firewall opens H-1B investigations without waiting for a complaint. These checkpoints come from Shire Human Genetic Therapies Inc.'s own public LCA filings (FY2024–FY2026) — the same records an investigator pulls first.

1 need attention3 to watch3 clear
Needs attention
9 certified LCAs (9 positions) end within 180 days

Next end date: 2026-11-12. Employing an H-1B worker past the LCA end date without a new certified LCA is a strict-liability violation — the replacement LCA must be certified before the I-129 extension is filed.

Auditor asksWhich workers are on each expiring LCA, and is a superseding LCA already certified?
In your PAFSuperseding LCA, updated PAF entry and new posting notice for every position that continues.
Watch
5 worksites across 1 state

Each worksite needs its own 10-business-day LCA notice and a PAF record of that posting; a move to a new area of intended employment needs a new LCA before the worker starts there.

Auditor asksWhere is the posting record for each worksite, and were short-term placements tracked against the 30/60-day limits?
In your PAFPosting notices (or electronic-notice records) per worksite; new-worksite LCAs; placement log.
Watch
39% of positions are amendments or material changes

Frequent amendments usually mean worksite or role changes; each one must be covered by a new LCA before the change takes effect.

Auditor asksFor each amendment: what changed, on what date, and was the new LCA certified before that date?
In your PAFAmended LCAs with dates aligned to the actual change; updated PAF entries.
Watch
18% of LCAs denied or withdrawn (FY2024–FY2026)

Withdrawn or denied LCAs are normal in isolation; a high share suggests workers were moved between filings and the paper trail needs checking.

Auditor asksWere the workers on withdrawn LCAs re-covered by a valid certified LCA before continuing work?
In your PAFWithdrawal acknowledgements; superseding LCAs; PAF entries showing the transition.
Clear
19% of certified LCAs are at Wage Level I

Level I is the entry-level prevailing-wage tier and the band DOL's Project Firewall reviews first for misclassification (senior duties filed at an entry-level wage). The national share is 17%.

Auditor asksHow was Level I justified for each role — required education, experience and the actual duties performed?
In your PAFPrevailing-wage determination and wage-level worksheet for every Level I LCA.
Clear
4% of LCAs offer a wage within 2% of the prevailing wage

Median offered wage is 11% above the DOL prevailing wage across 28 recent certified LCAs. Paying at the floor is lawful, but it invites the question of whether the wage level itself is right.

Auditor asksShow the actual wage paid (payroll) matches or exceeds the LCA wage for every worker, including benched time.
In your PAFActual-wage memorandum and pay records per LCA; wage-level rationale where the offered wage equals the PW.
Clear
Not H-1B dependent (per LCA attestation)

No additional recruitment or non-displacement attestations apply.

Auditor asksDoes the current H-1B headcount still fall under the dependency threshold?
In your PAFHeadcount snapshot supporting the non-dependent attestation at each filing.
Are you Shire Human Genetic Therapies Inc.? Get the private PAF / LCA gap check.
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Public DOL disclosure data can lag actual filings by a quarter. Descriptive only — not legal advice.

For job seekers

Considering a job at Shire Human Genetic Therapies Inc.?

Does Shire Human Genetic Therapies Inc. sponsor H-1B visas?

Yes — Shire Human Genetic Therapies Inc. is an active H-1B sponsor, with 101 certified LCAs on file (FY2021–FY2026), including 6 in FY2026. The median certified salary is $123,000 (P25 $106,012, P75 $152,193). With a 27% transfer share, this employer actively accepts H-1B transfers. 100% of its certified filings meet or exceed the prevailing wage.

What to Know Before Applying to Shire Human Genetic Therapies Inc.

Salary range
Median $123,000, typical band $106,012–$152,193.
Transfers
27% of filings are transfers — this employer has an established H-1B transfer track record.
Typical locations
Lexington, MA, Cambridge, MA, Leexington, MA, CAMBRIDGE, MA.
Position type
100% of filings are full-time roles.
Common roles
Senior Validation Engineer, Senior Downstream Development Engineer, Senior Downstream Engineer I.
Benchmark this employer in the H-1B database →
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Frequently asked questions

Yes. Shire Human Genetic Therapies Inc. has 101 certified Labor Condition Applications (LCAs) on file with the U.S. Department of Labor (FY2021–FY2026).

The median sponsored salary is $123,000, with a typical P25–P75 band of $106,012–$152,193 across certified LCAs.

Yes — 27% of its LCA filings are change-of-employer (transfer) cases, indicating an active transfer pipeline.

No — the employer attests it is not H-1B dependent on its LCA filings.

Shire Human Genetic Therapies Inc. filed 6 certified LCAs in FY2026, the most recent fiscal year of U.S. DOL disclosure data.

Top worksites include Lexington, MA, Cambridge, MA, Leexington, MA, CAMBRIDGE, MA.
Sponsorship data

Shire Human Genetic Therapies Inc. H-1B data at a glance

Executive Summary

Shire Human Genetic Therapies Inc. H-1B sponsorship at a glance, from public U.S. DOL LCA disclosure data (FY2021–FY2026).

  • Median certified salary is $123,000, typically $106,012–$152,193 (P25–P75).
  • 100% of certified filings are at or above the DOL prevailing wage.
  • Change-of-employer (transfer) share is 27% — workers actively transfer to this employer.
  • Worksite footprint spans 1 state and 5 cities.
  • Most-sponsored roles: Senior Validation Engineer, Senior Downstream Development Engineer, Senior Downstream Engineer I.
  • Filed 6 certified LCAs in FY2026, the most recent disclosure year.

Certified LCAs are a prerequisite to H-1B petitions, not visa approvals; one LCA can cover multiple workers. Descriptive only — not legal advice.

Salary Distribution

$68,000
$225,000
P25$106,012
Median$123,000
P75$152,193

The shaded band is the middle half of certified salaries (P25–P75); the bar spans the lowest to highest certified salary.

100% of certified filings at or above the DOL prevailing wage.

Wage Level Distribution

Level I
19%
Level II
29%
Level III
13%
Level IV
39%

Levels I–IV are DOL prevailing-wage experience tiers; 52% of filings are senior-level (III–IV).

Filing history

LCA filings by fiscal year

Certified LCAs per year

FY2021
51
FY2022
14
FY2023
8
FY2024
17
FY2025
5
FY2026
6
Fiscal yearCertifiedDeniedWithdrawnTotal
FY2021510657
FY2022140418
FY2023801018
FY2024170421
FY20255027
FY20266006

Case dispositions from the U.S. DOL OFLC disclosure files. Withdrawn are LCAs that were certified and later withdrawn by the employer; they still count toward Total.

See a single year in detail:
FY2021 ›FY2022 ›FY2023 ›FY2024 ›FY2025 ›FY2026 ›

All LCA filings

90 filings
Job titleSalaryLevelLocationFiledStatus
Senior Process Validation Engineer I
I-200-26167-021590
$113,074/yrIILexington, MAJun 16, 2026Certified
Sr. Validation Engineer
I-200-26161-003179
$133,120/yrIIILexington, MAJun 10, 2026Certified
Project Management, Principal Analyst
I-200-26148-959786
$140,000/yrIILexington, MAMay 28, 2026Certified
Senior Validation Engineer I
I-200-26147-954582
$112,000/yrIILexington, MAMay 27, 2026Certified
Automation Hardware Engineer
I-200-26126-874442
$196,950/yrIVLexington, MAMay 06, 2026Certified
Validation Manager
I-200-25345-474475
$169,914/yrIVLexington, MADec 11, 2025Certified
Quality Manager - QA Operations
I-200-25232-256705
$147,732/yrIVLexington, MAAug 20, 2025Certified
Automation Engineer
I-200-25217-223292
$93,000/yrILexington, MAAug 05, 2025Certified
Senior Process Validation Engineer I
I-200-25197-178709
$109,781/yrIILexington, MAJul 16, 2025Certified
Director, Head of Manufacturing Science Downstream
I-200-25104-861147
$225,000/yrIVLexington, MAApr 14, 2025Certified
Senior Manager, Process Engineering
I-200-25062-739454
$160,774/yrILexington, MAMar 03, 2025Certified
QC Analyst II
I-200-24241-299385
$85,000/yrIVLexington, MAAug 28, 2024Certified
Project Portfolio Specialist
I-200-24221-253734
$126,560/yrIILexington, MAAug 08, 2024Certified
Validation Engineer - Process Validation, Professional II
I-200-24185-173618
$101,706/yrIILexington, MAJul 03, 2024Certified
Senior Engineer II
I-200-24166-112481
$138,820/yrIIILexington, MAJun 14, 2024Certified
CMC Submission Lead
I-200-24143-025204
$97,000/yrIIILexington, MAMay 22, 2024Certified
Scientist
I-200-24123-952053
$106,012/yrIILexington, MAMay 02, 2024Certified
Team Lead, Device Regulatory Affairs, PDT BU
I-200-24082-825268
$210,250/yrIVLexington, MAMar 22, 2024Certified
Regulatory Lead
I-200-24068-782802
$152,193/yrIVCambridge, MAMar 08, 2024Certified
Senior Validation Engineer II
I-200-24064-768247
$154,166/yrIIILexington, MAMar 04, 2024Certified
Regulatory Lead
I-200-24060-758571
$152,193/yrIVCambridge, MAFeb 29, 2024Certified
Director, Quality Risk Management
I-200-24038-701760
$197,450/yrIVLexington, MAFeb 07, 2024Certified
Product Quality Lead
I-200-24033-689241
$195,000/yrIVLexington, MAFeb 02, 2024Certified
Product Quality Lead
I-200-24009-628477
$195,000/yrIVLexington, MAJan 09, 2024Withdrawn
Digital Analyst
I-200-23321-510177
$130,000/yrIIFitchburg, MANov 17, 2023Certified

One row per LCA case (its latest version), from U.S. DOL OFLC disclosure data. Salaries are the offered wage, converted to a yearly figure. Certified LCAs are not visa approvals.

Every certified LCA needs its own Public Access File. Get the private gap check →
Sponsorship insights

How Shire Human Genetic Therapies Inc. sponsors H-1B talent

Petition Mix

New employment  12%Transfer (change of employer)  27%Continued employment  23%Amendments & other  39%
High transfer share (27%) — H-1B workers actively change employers to join Shire Human Genetic Therapies Inc..

Worker positions by LCA filing purpose, summed across FY2021–FY2026 disclosure records.

Filing Activity by Month

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec

Most active filing months: May and Apr — useful for timing transfer conversations.

Compliance Posture

H-1B Dependent
No
Willful Violator
No
Full-Time Positions
100%
At/Above Prevailing Wage
100%

Attestations from the employer's own LCA filings (Form ETA-9035), as disclosed by the U.S. DOL.

Roles & geography

Top sponsored roles & worksites

Top job titles

Senior Validation Engineer
7 · $118,963
Senior Downstream Development Engi
4 · $120,242
Senior Downstream Engineer I
4 · $105,183
Senior Reliability Engineer
4 · $123,000
Associate Director – Regulatory La
3 · $145,528

Top worksite locations

1 state · 5 cities

Lexington, MA
95
Cambridge, MA
25
Leexington, MA
3
CAMBRIDGE, MA
1
Fitchburg, MA
1
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Shire Human Genetic Therapies Inc. · audit readiness
1 need attention3 to watch3 clear
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