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H-1B Data › Employers › Karyopharm Therapeutics Inc.
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H-1B Sponsor Profile

Karyopharm Therapeutics Inc. — H-1B Visa Sponsorship Data

39 certified Labor Condition Applications on file with the U.S. Department of Labor, FY2021–FY2026.

NEWTON, MAActive FY2021–FY2026Transfer-FriendlyFull-Time RolesNot H-1B Dependent
● Data current through FY2026 · sourced from U.S. DOL OFLC, updated quarterly
I work at Karyopharm Therapeutics Inc.See what a DOL auditor would ask about your filingsConsidering a job here?Salaries, transfers and where roles are based
Sponsors H-1B?
Yes
39 certified LCAs
FY2026 filings
4
most recent disclosure year
Median H-1B salary
$132,657
typical $120,000–$160,342
H-1B dependent?
No
per the employer's LCA attestation
Transfer share
33%
change-of-employer filings
Audit readiness Check another employer

3 items a DOL auditor would ask Karyopharm Therapeutics Inc. about

Since September 2025, DOL's Project Firewall opens H-1B investigations without waiting for a complaint. These checkpoints come from Karyopharm Therapeutics Inc.'s own public LCA filings (FY2024–FY2026) — the same records an investigator pulls first.

1 need attention2 to watch2 clear
Needs attention
11 worksites across 9 states

Each worksite needs its own 10-business-day LCA notice and a PAF record of that posting; a move to a new area of intended employment needs a new LCA before the worker starts there.

Auditor asksWhere is the posting record for each worksite, and were short-term placements tracked against the 30/60-day limits?
In your PAFPosting notices (or electronic-notice records) per worksite; new-worksite LCAs; placement log.
Watch
55% of LCAs offer a wage within 2% of the prevailing wage

Median offered wage is 1% above the DOL prevailing wage across 11 recent certified LCAs. Paying at the floor is lawful, but it invites the question of whether the wage level itself is right.

Auditor asksShow the actual wage paid (payroll) matches or exceeds the LCA wage for every worker, including benched time.
In your PAFActual-wage memorandum and pay records per LCA; wage-level rationale where the offered wage equals the PW.
Watch
21% of LCAs denied or withdrawn (FY2024–FY2026)

Withdrawn or denied LCAs are normal in isolation; a high share suggests workers were moved between filings and the paper trail needs checking.

Auditor asksWere the workers on withdrawn LCAs re-covered by a valid certified LCA before continuing work?
In your PAFWithdrawal acknowledgements; superseding LCAs; PAF entries showing the transition.
Clear
0% of certified LCAs are at Wage Level I

Level I is the entry-level prevailing-wage tier and the band DOL's Project Firewall reviews first for misclassification (senior duties filed at an entry-level wage). The national share is 17%.

Auditor asksHow was Level I justified for each role — required education, experience and the actual duties performed?
In your PAFPrevailing-wage determination and wage-level worksheet for every Level I LCA.
Clear
Not H-1B dependent (per LCA attestation)

No additional recruitment or non-displacement attestations apply.

Auditor asksDoes the current H-1B headcount still fall under the dependency threshold?
In your PAFHeadcount snapshot supporting the non-dependent attestation at each filing.
Are you Karyopharm Therapeutics Inc.? Get the private PAF / LCA gap check.
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Public DOL disclosure data can lag actual filings by a quarter. Descriptive only — not legal advice.

For job seekers

Considering a job at Karyopharm Therapeutics Inc.?

Does Karyopharm Therapeutics Inc. sponsor H-1B visas?

Yes — Karyopharm Therapeutics Inc. sponsors H-1B workers, with 39 certified LCAs on file (FY2021–FY2026), including 4 in FY2026. The median certified salary is $132,657 (P25 $120,000, P75 $160,342). With a 33% transfer share, this employer actively accepts H-1B transfers. 100% of its certified filings meet or exceed the prevailing wage.

What to Know Before Applying to Karyopharm Therapeutics Inc.

Salary range
Median $132,657, typical band $120,000–$160,342.
Transfers
33% of filings are transfers — this employer has an established H-1B transfer track record.
Typical locations
Newton, MA, NEWTON, MA, Centerville, VA, Edgewater, NJ.
Position type
100% of filings are full-time roles.
Common roles
Senior Medical Director, Pharmacovigil, Clinical Data Manager, Senior Manager, Regulatory Operations.
Benchmark this employer in the H-1B database →
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Frequently asked questions

Yes. Karyopharm Therapeutics Inc. has 39 certified Labor Condition Applications (LCAs) on file with the U.S. Department of Labor (FY2021–FY2026).

The median sponsored salary is $132,657, with a typical P25–P75 band of $120,000–$160,342 across certified LCAs.

Yes — 33% of its LCA filings are change-of-employer (transfer) cases, indicating an active transfer pipeline.

No — the employer attests it is not H-1B dependent on its LCA filings.

Karyopharm Therapeutics Inc. filed 4 certified LCAs in FY2026, the most recent fiscal year of U.S. DOL disclosure data.

Top worksites include Newton, MA, NEWTON, MA, Centerville, VA, Edgewater, NJ.
Sponsorship data

Karyopharm Therapeutics Inc. H-1B data at a glance

Executive Summary

Karyopharm Therapeutics Inc. H-1B sponsorship at a glance, from public U.S. DOL LCA disclosure data (FY2021–FY2026).

  • Median certified salary is $132,657, typically $120,000–$160,342 (P25–P75).
  • 100% of certified filings are at or above the DOL prevailing wage.
  • Change-of-employer (transfer) share is 33% — workers actively transfer to this employer.
  • Worksite footprint spans 9 states and 11 cities.
  • Most-sponsored roles: Senior Medical Director, Pharmacovigilan, Clinical Data Manager, Senior Manager, Regulatory Operations.
  • Filed 4 certified LCAs in FY2026, the most recent disclosure year.

Certified LCAs are a prerequisite to H-1B petitions, not visa approvals; one LCA can cover multiple workers. Descriptive only — not legal advice.

Salary Distribution

$86,781
$265,000
P25$120,000
Median$132,657
P75$160,342

The shaded band is the middle half of certified salaries (P25–P75); the bar spans the lowest to highest certified salary.

100% of certified filings at or above the DOL prevailing wage.

Wage Level Distribution

Level I
0%
Level II
33%
Level III
24%
Level IV
43%

Levels I–IV are DOL prevailing-wage experience tiers; 67% of filings are senior-level (III–IV).

Filing history

LCA filings by fiscal year

Certified LCAs per year

FY2021
10
FY2022
8
FY2023
10
FY2024
1
FY2025
6
FY2026
4
Fiscal yearCertifiedDeniedWithdrawnTotal
FY2021100212
FY202280311
FY2023100616
FY20241012
FY20256028
FY20264004

Case dispositions from the U.S. DOL OFLC disclosure files. Withdrawn are LCAs that were certified and later withdrawn by the employer; they still count toward Total.

See a single year in detail:
FY2021 ›FY2022 ›FY2023 ›FY2024 ›FY2025 ›FY2026 ›

All LCA filings

37 filings
Job titleSalaryLevelLocationFiledStatus
Associate Director, Regulatory Operations
I-200-26079-719715
$188,500/yrIIINewton, MAMar 20, 2026Certified
Senior Manager, Regulatory Operations
I-200-26079-718687
$190,215/yrIIINewton, MAMar 20, 2026Certified
Senior Manager, Regulatory Operations
I-200-26079-719694
$188,500/yrIIINewton, MAMar 20, 2026Certified
Sr Scientist, Analytical Chemistry
I-200-25316-401122
$153,480/yrIVNewton, MANov 12, 2025Certified
Senior Clinical Data Manager
I-200-25260-315964
$132,656/yrIVFarmington, ARSep 17, 2025Certified
Manager, Regulatory Operations
I-200-25190-161262
$139,932/yrIVMorrisville, NCJul 09, 2025Certified
Senior Statistical Programmer 1
I-200-25111-886404
$123,965/yrIIINewton, MAApr 21, 2025Certified
Sr Clinical Data Manager
I-200-25107-873684
$132,717/yrIIHaymarket, VAApr 16, 2025Certified
GCP Documentation Specialist
I-200-25105-866369
$96,616/yrIINewton, MAApr 15, 2025Certified
Senior Biostatistician
I-200-25009-606996
$187,044/yrIVNewton, MAJan 09, 2025Certified
Senior Clinical Data Manager
I-200-23338-541435
$124,500/yrIIIFarmington, ARDec 04, 2023Certified
Sr. Clinical Trial Manager
I-200-23202-205948
$160,000/yrIVNewton, MAJul 21, 2023Certified
Manager, Regulatory Operations
I-200-23104-934396
$130,000/yrIVDes Plaines, ILApr 14, 2023Certified
Associate Director, IST Operations
I-200-23090-892502
$124,747/yrIVEdgewater, NJMar 31, 2023Certified
Manager Regulatory Operations
I-200-23089-890084
$109,745/yrIVNewton, MAMar 30, 2023Certified
Senior Manager, Regulatory Operations
I-200-23089-889988
$160,685/yrIIINewton, MAMar 30, 2023Certified
Senior Manager, Regulatory Operations
I-200-23089-889620
$170,000/yrIIINewton, MAMar 30, 2023Certified
Sr Scientist, Analytical Chemistry
I-200-23089-889509
$143,763/yrIVNewton, MAMar 30, 2023Certified
Senior Clinical Data Manager
I-200-23005-683715
$120,000/yrIIIApex, NCJan 05, 2023Certified
Sr Clinical Data Manager
I-200-22284-523514
$120,000/yrIICenterville, VAOct 11, 2022Certified
Associate Director/Director, Clinical Pharmacology and DMPK
I-200-22194-349768
$170,475/yrIVMerced, CAJul 13, 2022Certified
Sr Scientist Bioanalytical
I-200-22112-096993
$145,000/yrIVNewton, MAApr 22, 2022Certified
GCP Documentation Specialist
I-200-22096-043612
$86,781/yrIINewton, MAApr 06, 2022Certified
Manager, Regulatory Affairs
I-200-22049-913378
$120,000/yrIINewton, MAFeb 18, 2022Certified
Senior Medical Director, Pharmacovigilance
I-200-22033-872422
$265,000/yrIVNewton, MAFeb 02, 2022Certified

One row per LCA case (its latest version), from U.S. DOL OFLC disclosure data. Salaries are the offered wage, converted to a yearly figure. Certified LCAs are not visa approvals.

Every certified LCA needs its own Public Access File. Get the private gap check →
Sponsorship insights

How Karyopharm Therapeutics Inc. sponsors H-1B talent

Petition Mix

New employment  11%Transfer (change of employer)  33%Continued employment  38%Amendments & other  18%
High transfer share (33%) — H-1B workers actively change employers to join Karyopharm Therapeutics Inc..

Worker positions by LCA filing purpose, summed across FY2021–FY2026 disclosure records.

Filing Activity by Month

Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec

Most active filing months: Mar and Apr — useful for timing transfer conversations.

Compliance Posture

H-1B Dependent
No
Willful Violator
No
Full-Time Positions
100%
At/Above Prevailing Wage
100%

Attestations from the employer's own LCA filings (Form ETA-9035), as disclosed by the U.S. DOL.

Roles & geography

Top sponsored roles & worksites

Top job titles

Senior Medical Director, Pharmacov
5 · $265,000
Clinical Data Manager
4 · $100,942
Senior Manager, Regulatory Operati
4 · $177,350
Sr Clinical Data Manager
4 · $123,179
Manager, Regulatory Affairs
3 · $120,000

Top worksite locations

9 states · 11 cities

Newton, MA
34
NEWTON, MA
5
Centerville, VA
3
Edgewater, NJ
2
Farmington, AR
2
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Karyopharm Therapeutics Inc. · audit readiness
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